---
title: 编译和安装
description: "1. 使用PuTTY工具，以root用户登录服务器。"
url: https://www.hikunpeng.com/document/detail/zh/kunpenghpcs/hpcindapp/prtg-osc/kunpengvep_02_0007.html
sourcePath: /source/zh/kunpenghpcs/hpcindapp/prtg-osc/kunpengvep_02_0007.html
indexId: 68aa043b4cde4ae14dc1fdd6f53999ffdc2af05c7fd6ab30ed331c7f459e661965
---
# 编译和安装

#### 操作步骤

1. 使用PuTTY工具，以root用户登录服务器。
2. 执行以下命令解压安装包。

```
tar -zxvf 104.3.tar.gz
```


3. 执行以下命令进入解压后的目录。

```
cd ensembl-vep-release-104.3
```


4. 安装并使用cpanm工具下载依赖包。

```
yum install -y perl perl-App-cpanminus.noarch perl-core perl-DBD-MySQL perl-Try-Tiny.noarch
cpanm Archive::Zip
cpanm DBI
cpanm Bio::Root::Version
cpanm Bio::DB::HTS::Tabix
cpanm HTTP::Tiny
```


5. 执行以下命令进行编译安装。

```
perl INSTALL.pl  --NO_HTSLIB
```


  回显信息中的三处选项请选择“n”。

```
Do you want to install any cache files (y/n)? n
Skipping cache installation
The VEP can use FASTA files to retrieve sequence data for HGVS notations and reference sequence checks.
FASTA files will be stored in /root/.vep
Do you want to install any FASTA files (y/n)? n
Skipping FASTA installation - Exiting
The VEP can use plugins to add functionality and data.
Plugins will be installed in /root/.vep/Plugins
Do you want to install any plugins (y/n)? n
Skipping plugin installation
```


6. （可选）下载缓存文件。

```
cd /root/.vep
wget http://ftp.ensembl.org/pub/release-104/variation/indexed_vep_cache/homo_sapiens_vep_104_GRCh38.tar.gz --no-check-certificate
tar xvf homo_sapiens_vep_104_GRCh38.tar.gz
```