Introduction

TopHat2 is a program that quickly splices and maps RNA-Seq data. It uses the ultra-fast high-throughput short-read comparison program to compare RNA-Seq information to the mammalian size genome, then the mapping results are analyzed to identify the splice points between exons. TopHat is the result of a joint development of the University of Maryland Center for Bioinformation and Computer Biology, the Departments of Mathematics and Molecular and Cell Biology of the University of California, Berkeley, and the Harvard Department of Stem Cell and Regenerative Biology.

For more information, visit the official TopHat2 website.

Programming language: C

Brief description: a program that quickly splices and maps RNA-Seq data

Open source license: Boost Software License 1.0