Introduction

GUIDEseq implements GUIDE-seq and PEtag-seq analysis workflow including functions for filtering UMI and reads with low coverage, obtaining unique insertion sites (proxy of cleavage sites), estimating the locations of the insertion sites, aka, peaks, merging estimated insertion sites from plus and minus strand, and performing off target search of the extended regions around insertion sites.

For more information, visit the GUIDEseq official website.

Programming language: R

Brief description: GUIDEseq implements GUIDE-seq and PEtag-seq analysis workflow.

Open source license: GPL 3.0