Introduction

MAGeCKFlute provides several strategies to remove potential biases within sgRNA-level read counts and gene-level beta scores. The downstream analysis with the package includes identifying essential, non-essential, and target-associated genes, and performing biological functional category analysis, pathway enrichment analysis and protein complex enrichment analysis of these genes. The package also visualizes genes in multiple ways to benefit users exploring screening data. Collectively, MAGeCKFlute enables accurate identification of essential, non-essential, and targeted genes, as well as their related biological functions.

For more information, visit the MAGeCKFlute website.

Programming language: R

Brief description: Provides several strategies to remove potential biases within sgRNA-level read counts and gene-level beta scores.

Open source license: custom open source license

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